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pentobarbital will lower the level or influence of erlotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will lessen the extent or impact of pitolisant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Pitolisant exposure is reduced by 50% if coadminister